Press Release: Loss of protective heart failure protein linked to critical limb ischemia S100A1 could be a potential therapeutic target in critical limb ischemiato promote revascularization, say Thomas Jefferson University researchers from the Center for Translational Medicine Quote: Restoring diminished levels of a protein shown to prevent and reverse heart failure damage could also have therapeutic applications for patients with critical limb ischemia (CLI), suggests a new preclinical study published online October 9 in Circulation Research from researchers at the Center for Translational Medicine at Thomas Jefferson University . Low levels of the protein S100A1 have been linked to congestive heart failure and high blood pressure, and now appear to be associated with critical lower limb ischemia, a condition found in type 2 diabetic patients where blood flow to legs is cut off, often resulting in amputation
See the rest here:
Critical limb ischemia
